November 25, 2015
After years of painstaking research, cell, gene and tissue therapies are turning in unprecedented evidence of efficacy in phase I/II. Unlike the old model, where the sole focus would now be on phase III, companies need to work simultaneously on manufacturing, logistics, pricing and getting the product to the patient, says Keith Thompson.

November 25, 2015
Positive data in the phase III trial of TiGenix’s Cx601 allogeneic cell therapy indicates it could provide a one-off treatment for complex perianal fistulas, a complication of Crohn’s disease. The results open up a completely new avenue for treatment of patients who do not respond to existing therapies, says Eduardo Bravo, CEO of Tigenix.

November 19, 2015
With more companies advancing innovative therapies to the end of phase II, the funding requirements of European biotech are spiralling. A new initiative is required to create large and liquid funds to support the next stage of growth and ensure Europe reaps the benefits – both medical and commercial – of its excellent research, says Emil Pot.

November 12, 2015 - London
After huge investment in the basic science and translation to the clinic, Europe’s advanced therapies companies are accumulating data, which indicate these products have an unprecedented effect. Now effort is needed to develop manufacturing, organise logistics, agree reimbursement and ensure patients get the benefits. Vital Transformation reports for EBE from the ARM Conference.